Antimalarial Atovaquone May Improve Lung Cancer Treatment Outcomes
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چکیده
منابع مشابه
Antimalarial pharmacology and therapeutics of atovaquone
Atovaquone is used as a fixed-dose combination with proguanil (Malarone) for treating children and adults with uncomplicated malaria or as chemoprophylaxis for preventing malaria in travellers. Indeed, in the USA, between 2009 and 2011, Malarone prescriptions accounted for 70% of all antimalarial pre-travel prescriptions. In 2013 the patent for Malarone will expire, potentially resulting in a w...
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Recently, it was reported that sera from healthy volunteers given atovaquone-proguanil (Malarone) inhibited parasite transmission and asexual blood stage development for up to 6 weeks after treatment (1). The lengthy persistence of drug activity was quite unexpected because earlier studies had shown that proguanil and atovaquone had elimination halflives of about 14 to 20 h (2–4, 10, 11) and 2 ...
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ژورنال
عنوان ژورنال: Oncology Times
سال: 2021
ISSN: 0276-2234
DOI: 10.1097/01.cot.0000749928.39408.89